BETA LAUNCHING APRIL 2026

The intelligent front door to your safety database.

AE Connect captures adverse event reports through a guided intake form, uses AI to code and triage each case, and sends structured data directly into Veeva, Argus, or your existing safety system, no rekeying, no delays.

The Problem

Adverse events get lost in the gap between intake and your safety database.

Reporters submit AEs through emails, phone calls, paper forms, and portals that don't talk to each other. PV teams manually retype everything into Argus or Veeva. The result? Delays, errors, and regulatory risk.

Manual rekeying eats 60%+ of case processing time

Safety teams spend the majority of their time transcribing data from intake forms into safety databases rather than evaluating the actual adverse event. Every manual entry is a chance for error.

🔌

Intake systems don't connect to safety databases

Most biotechs capture AE reports through disconnected channels, email, phone, web forms, none of which feed directly into Veeva Vault Safety, Argus, or other ICSR systems. The data gap is where compliance risk lives.

📋

Inconsistent reporting means incomplete cases

Without a structured, guided intake, reporters skip fields, use free text where codes belong, and omit critical details. PV teams chase follow-ups instead of processing cases.

🏢

Small biotechs can't afford full PV platforms

Enterprise safety suites cost $500K+ and take 12+ months to implement. Pre-commercial and small biotechs need the intake and triage layer without replacing their entire safety stack.

The Intake Form

A guided, 5-step reporter form that captures complete cases the first time.

AE Connect walks reporters through a structured intake, patient info, product details, event description, reporter information, and review, so every submission arrives ready for triage.

AE Connect, Report an Adverse Event STEP 3 OF 5
STEP 3
Event Information
Patient experienced moderate headache and dizziness approximately 2 hours after first dose administration...
02/18/2026
Non-serious
Recovering / Resolving
No
Hypertension (controlled), Type 2 Diabetes
📝

5-Step Guided Flow

Patient details, product info, event description, reporter identity, and confirmation, with progress tracking and field validation at every step.

🌐

Multi-Channel Capture

Public web portal, internal forms for HCPs and field teams, and email-to-case ingestion, all feeding into the same structured pipeline.

🏷

Configurable Per Organization

Custom branding, product lists, field requirements, and consent language. Each organization gets its own intake URL and form configuration.

📱

Mobile-First Design

Reporters in the field, HCPs, patients, sales reps, can submit from any device. Responsive design with offline-capable draft saving.

🔒

Compliance Built In

HIPAA-ready data handling, consent capture, audit trails on every submission, and 21 CFR Part 11 electronic signature support.

Instant AI Triage

The moment a report is submitted, AI auto-codes MedDRA terms, assesses seriousness and causality, and flags cases that need immediate attention.

Integrations

Connects directly to the safety databases you already use.

AE Connect isn't a replacement for your safety system, it's the intelligent intake layer that feeds structured, AI-triaged cases directly into Veeva Vault Safety, Oracle Argus, and other ICSR databases. No rekeying. No copy-paste.

Reporters
AE Reports
HCPs, patients, field teams,
call centers, partner sites
Intake + AI Triage
AE Connect
Structured capture, MedDRA coding,
causality assessment, prioritization
Your Safety Database
Veeva · Argus · ICSR
Cases arrive coded, triaged,
and ready for medical review
V

Veeva Vault Safety

Direct API integration with Vault Safety. Cases flow from AE Connect into your Vault inbox as structured ICSRs with MedDRA coding intact.

INTEGRATION READY
A

Oracle Argus Safety

Submit triaged cases to Argus via E2B(R3) XML or direct API. Mapped fields, coded terms, and seriousness assessments transfer automatically.

INTEGRATION READY
E2B

E2B(R3) XML Export

Generate ICH-compliant E2B(R3) XML for any safety database or direct regulatory submission to FDA MedWatch and EudraVigilance.

BETA
API

Open REST API

For safety databases not listed here, use our documented REST API to pull structured case data into any system your team uses.

COMING SOON

🔄 What Gets Transferred

Every field captured in the intake form and enriched by AI triage flows into your safety database as structured data:

Patient demographics, medical history, and concomitant medications
AI-coded MedDRA Preferred Terms and Lowest Level Terms
Seriousness criteria assessment and causality determination
Product information with suspect/concomitant classification
Reporter details, narrative text, and supporting documents

🛡 Integration Architecture

AE Connect is designed to complement, not replace, your existing safety infrastructure:

One-way data push, AE Connect sends, your safety DB remains system of record
Field mapping configurable per organization and safety database
Encrypted transmission with full audit trail of every data transfer
Manual review gate before submission, nothing goes to your DB unseen
Retry logic and error handling for failed transmissions with admin alerts
How It Works

From report to safety database in minutes, not days.

AE Connect automates the journey from initial adverse event report to structured ICSR in your safety database, with AI assistance and human oversight at every step.

1

Reporter Submits

HCPs, patients, or field reps complete the guided 5-step intake form via web portal, mobile, or internal submission.

2

AI Triages & Codes

AI engine auto-codes MedDRA terms, assesses seriousness and expectedness, runs causality analysis, and flags priority cases.

3

PV Specialist Reviews

Your safety team reviews the AI analysis, confirms or adjusts coding, and approves the case for submission to your safety database.

4

Syncs to Your Database

Approved cases push directly into Veeva Vault Safety, Oracle Argus, or via E2B(R3) XML, fully structured and audit-trailed.

AI-Powered Triage

AI that understands pharmacovigilance.

AE Connect's triage engine is purpose-built for drug safety, not a generic chatbot. It reads narrative text, identifies adverse events, codes to MedDRA, and assesses causality using the same frameworks your PV team uses.

🧬

MedDRA Auto-Coding

Maps free-text event descriptions to MedDRA Preferred Terms and Lowest Level Terms. Suggests multiple candidates ranked by confidence.

⚖️

Causality Assessment

Evaluates temporal relationship, dechallenge/rechallenge, and known drug profile to generate a preliminary causality determination.

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Seriousness & Priority

Classifies seriousness criteria per ICH E2D guidelines and flags expedited reporting cases (15-day, 7-day) automatically.

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Narrative Generation

Drafts a structured case narrative from the submitted data, ready for your team to review, edit, and include in the ICSR.

Product Roadmap

Building the complete safety intake platform.

AE Connect is our first product, purpose-built for adverse event intake and triage. Next: product quality complaints.

APRIL 2026

AE Connect, Private Beta

Guided 5-step intake form, AI-powered MedDRA coding and causality assessment, case management dashboard, and Veeva/Argus integration.

Intake Form AI Triage Veeva Integration Argus Integration RBAC
APRIL 2027

PQC Connect, Product Quality Complaints

Structured complaint intake, investigation workflows, CAPA tracking, and cross-linking with AE Connect for cases that involve both safety and quality events.

Complaint Intake Investigation Workflow CAPA Tracking AE Cross-Link

Stop rekeying adverse events.
Start connecting your intake to your safety database.

Join the private beta and see how AE Connect captures, triages, and delivers structured cases directly into Veeva or Argus.